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Global Tissue Plasminogen Activator (TPA) Market

Dec. 1, 2019

Global Tissue Plasminogen Activator (TPA) Market, By Dosage (2mg, 50mg, and 100mg), By Administration Route (Intravenous and Regional Intra-Arterial), Application (Blood Clots, Pulmonary Embolism, Myocardial Infarction, and Stroke, Others), By Region (North America, Latin America, Europe, Asia-Pacific, and Middle East and Africa) - Global Forecast, 2020-2025.

Report Code :FMR275      
Industry : Biotechnology
Pages :205 Pages
Format :   PPT Format   PDF Format

The global tissue plasminogen activator (TPA) market was valued at US$ xx million in the year 2019. This market is estimated to be valued at US$ xx million in the year 2020, and is expected to reach US$ xx million by the year 2025, with an estimated CAGR of xx% during the forecast period (2020-2025). Tissue plasminogen activator (tPA) is an enzyme associated with clot breakdown (fibrinolysis) in the blood. It is a serine protease present in endothelial cells. With the aid of serine protease, the conversion of plasminogen to plasmin is catalyzed. Serine protease is an essential enzyme in the degradation of clots. The increasing number of acute ischemic stroke patients are expected to drive the tissue plasminogen activator market growth. For instance, in 2016, according to journal of Missouri medicine, ischemic strokes are the most common (≈85%) of the total of strokes, the rest being hemorrhagic that include cerebral and subarachnoid (≈15%).

Table 1. Global Tissue Plasminogen Activator Market Synopsis

Parameters

Description

Market Value (US$ Mn) for the Period

2018-2025

Base Year

2019

Forecast Period

2020-2025

Market Segmentation (By Dosage)

2mg, 50mg, and 100mg

Market Segmentation (By Administration Route)

Intravenous and Regional Intra-Arterial

Market Segmentation (Application)

Blood Clots, Pulmonary Embolism, Myocardial Infarction, and Stroke, Others

Regions Covered

North America, Latin America, Europe, Asia-Pacific, Middle East & Africa,

Key Players Coverage

Genentech, Sigma-Aldrich, Taj Pharmaceuticals, Bayer AG, Abcam, Calbiochem, Merck & Company, Roche, Sekisui Diagnostics, and Cadila Healthcare Ltd. among others.

Key Insights

  • Latest Updates
  • Analyst Views
  • Future Outlook of the Market

Market Dynamics

The global market for plasminogen activator tissue keeps on growing at a rapid pace. This rise can be due to strengthened health care services and demand for technologically advanced stroke products in developing countries.  Stroke is a leading cause of death and disability both globally and in the U.S., approximately 800,000 people experience a stroke each year in U.S.. Another factor affecting market share is the rising prevalence of stroke incidences in the growing geriatric population. According to Public Health England (PHE), in 2018, approximately 38% of individuals with strokes were between the ages of 40 and 69 globally.

Moreover, tissue plasminogen activator market growth can be hampered by substitute product approvals by the Food and Drug Administration (FDA). For instance, after the approval of stent retriever by the FDA, in 2012, the global tissue plasminogen activator market growth was affected, since tPA is not effective for major blood clots in comparison to the stent retriever thrombectomy.

Figure 1. Tissue Plasminogen Activator Market Scenario Forecast (Likely, Conservative, and Optimistic Scenario), 2019 and 2025 (US$ Mn)

Note: The above figure is shown for illustrative purposes only, the actual data may vary and will be incorporated in the report.

North America is the world leader in the tissue plasminogen activator market, owing to increasing awareness of stroke and huge expenditure on stroke treatment. For example, the American Heart Association (AHA) reported stroke costs as US$ 34 billion in the U.S. in 2017, which includes stroke therapy medications as well as health care facilities costs. Moreover, Asia-Pacific is expected to show the fastest growth over the projected period due to increase in penetration of new drugs and increased occurrence of blood clotting disorders, stroke, myocardial infarction, and pulmonary embolism.

Figure 2. Regional Analysis

Note: Above figure shown for illustrative purpose only, the actual data may vary and will be incorporated in the report.

Competitve Landscape

Key players in global tissue plasminogen activator market include Genentech, Sigma-Aldrich, Taj Pharmaceuticals, F. Hoffmann-La Roche Ltd, Bayer AG, Abcam, Calbiochem, Merck & Company, Roche, Sekisui Diagnostics, and Cadila Healthcare Ltd. among others. The leading market players are focused on innovation and new product launches. For instance, in April 2020, Beth Israel Deaconess Medical Center (BIDMC) announced that they are focusing on coming up with anticoagulant drug tPA which can aid in the treatment of respiratory failure in COVID-19 patients, alleviating the anticipated scarcity of ventilators in patients with serious COVID-19 infectious disease

Figure 3. Market Share of Key Players, 2019

 

Note: Above figure shown for illustrative purpose only, the actual data may vary and will be incorporated in the report.

By Dosage

  • 2mg
  • 50mg
  • 100mg

By Administration Route

  • Intravenous
  • Regional Intra-Arterial

By Application

  • Blood Clots
  • Pulmonary Embolism
  • Myocardial Infarction
  • Stroke
  • Others

By Region

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East & Africa
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Note: This report provides in-depth analysis of the global tissue plasminogen activator market and provides market size (US$ Million) and compound annual growth rate (CAGR %) for the forecast period (2020-2025), considering 2019, as the base year.

  • What are the trends adopted by key players in the global tissue plasminogen activator market?
  • What key factors are expected to increase the demand for global tissue plasminogen activator market during the forecast period 2020-2025?
  • What are the major challenges inhibiting the growth of the global tissue plasminogen activator market?
  • What is the total market value (US$ Mn) generated in global tissue plasminogen activator market by dosage in 2019 and what are the forecasts by 2025?
  • Which application is expected to dominate the global tissue plasminogen activator market in the coming years?
  • Which route of administration is expected to foster the tissue plasminogen activator market growth?
  • What was the total revenue generated by the global tissue plasminogen activator market across different regions (North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa) in 2019, along with CAGR (%) for the period (2020-2025)?
  • Who are the key players contributing to the growth of the global tissue plasminogen activator market, and what are the new strategies adopted by them to retain a market share in the industry?
  • What is the competitive strength of the key players in the global tissue plasminogen activator market?
  • What new products are going to be approved or launched in the coming years which may have huge impact on the market?
  • What insights are derived through the analysis of key players on following parameters: company overview, financial performance, product portfolio, geographical presence, key highlights, and strategies?

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